571 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... - TTP VS HUS ... implications : TTP ... confirmatory testing for TTP ... #Thrombotic #Microangiopathy
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Primary Thrombotic Microangiopathy ... Thrombocytopenic Purpura (TTP ... Primary #Thrombotic #Microangiopathy
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... TMA is due to TTP ... compliment-mediated TTP ... TTP is only TMA ... #Thrombotic #Microangiopathy
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Thrombocytopenic Purpura (TTP ... Diagnosis of TTP ... • Distinguish TTP ... TMA: Thrombotic microangiopathy ... Treatment of TTP
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Consumption: - Microangiopathy ... : DIC, TTP, HUS ... Antibody-mediated: ITP
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Mechanical Trauma (Microangiopathic ... - Thrombotic microangiopathy ... thrombocytopenic purpura (TTP
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
microangiopathies (TMA) - TTP ... Drug-induced thrombotic microangiopathy
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Schistocytes: Microangiopathic ... DIC, TTP, HUS)
Echocardiogram Windows - Nomenclature
Each view is described using three (3) components
1) Transducer Position or "Window"
Echocardiogram Windows ... Two-chamber #Echocardiogram ... Nomenclature #POCUS #cardiology ... #views #TTE #orientations
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Schistocytes DAT(-) → Microangiopathic ... hemolytic anemia (TTP