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geriatrics aids causes hematology neurology alzheimersdisease apml arterial associated blurry cardiology classification differentiation elderly embolism hand infections infectiousdiseases lewybody lung
Lewy Body Dementia: Pathogenesis and Clinical Findings Lewy Body Dementia is a sub-category of major or mild
neurocognitive disorders ... particularly affecting memory ... visuospatial function Core ... sleep behavior disorder ... #pathophysiology
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
neurocognitive disorders ... hydrocephalus, HIV ... Aphaso-apraxo-agnosia syndrome ... hallucinations - Movement disorders ... #Differential #
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
dementia Pathophysiology ... Encephalopathy Triad: • Memory ... Diagnosis: MRI ... The clinical syndrome ... #dementia #AIDS
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Clinical Findings Risk ... mutations - Down syndrome ... AlzheimersDisease #Dementia ... #pathophysiology ... #geriatrics #diagnosis
Differential Diagnosis: New-Onset Seizure in the Elderly STRUCTURAL: • Stroke/TIA, Subdural hematoma, mass • Traumatic Brain Injury
Differential Diagnosis ... tenfold increased risk ... • Sleep Disorders ... : REM behavior disorder ... #Differential #Diagnosis
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... : • Valvular disorders ... • Increased risk ... Acute Coronary Syndrome ... #Diagnosis #Pathophysiology
Blurry Vision - Differential Diagnosis Framework Anatomical Approach to Eye Disease: 1. Lids/Lashes 2. Extraocular Muscles/Motility 3. Conjunctiva/Sclera 4. Cornea 5. Anterior
Blurry Vision - Differential ... Diagnosis Framework ... • Sjögren’s syndrome ... retina or optic disk ... • HIV/AIDS or
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... Diagnosis Framework ... • Acquired Risk ... • Nephrotic Syndrome ... Venous #Arterial #pathophysiology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Attempt if high risk ... initiation • Differential ... • Steroids: IV
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
- Differential ... Diagnosis Framework ... Pneumonia: • 3 syndromes ... Pneumonia: • Risk ... of a "flu-like syndrome
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