15 results
Pathophysiology of Hemolytic Anemia
 - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects)
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Hemolytic Anemia - Defects ... and metabolic defects ... ) - Defects in ... rnembranes - Defects ... Hemolytic #Anemia #hematology
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Differential Diagnosis Algorithm ... Extrinsic RBC Defects ... Intrinsic RBC Defects ... : Membrane defects ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
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Differential Diagnosis Algorithm ... Abnormal Hgb & Hgb Defects ... Hgb - Membrane Defects ... - RBC Enzyme Defects ... #Causes #Hematology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Qualitative Platelet Defects ... Thrombasthenia • Defect ... Inherited #Platelet #Defects ... #comparison #table ... differential #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... , Other enzyme defects ... Unstable hemoglobin defects ... Glutathione metabolism defects ... #workup #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
with coagulation defects ... Severe coagulation defects ... AFLP #obstetrics #hematology ... diagnosis #table #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
with coagulation defects ... Severe coagulation defects ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
Diagnosis Framework Hematologic ... Unmasked Urea Cycle Defects ... Differential #Diagnosis #Pathophysiology
Interventional bronchoscopic and surgical treatments for chronic obstructive pulmonary disease (COPD). Overview of various therapies used
Additionally, the effects ... long-term outcomes or comparison ... VolumeReduction #Bullectomy #Algorithm
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
less common, only affects ... gastroenterology #algorithm ... gastroenterology #hepatology