41 results
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Clinical Manifestations ... of Systemic Lupus ... Manifestations #Signs ... #Symptoms #Rheumatology ... #Diagnosis
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
, Drug-induced Lupus ... SLE), Sjogren's Syndrome ... Kumfer @AnnKumfer #Antinuclear ... ANA #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Associated with skin ... #SLE #Summary #diagnosis ... #rheumatology #
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #differential #diagnosis ... #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... -15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... erythematosus #diagnosis ... #rheumatology #
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... likely it will be clinically ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Combination of Skin Findings and Arthritis in Pediatrics Patient - Differential Diagnosis
Malar rash: 
 • A
- Differential Diagnosis ... migrans: • Target sign ... gabrieltalledop #dermatology ... #differential #diagnosis ... #peds #pediatrics
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... ) • Systemic lupus ... cases • Sjögren syndrome ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
is a clinical dermatological ... Stevens-Johnson Syndrome ... syndrome, caused ... differentiating between the diagnosis ... #TEN #Dermatology