27 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Investigation of Abnormal ... Coagulation Tests ... #Abnormal #APTT ... #Laboratory #Hematology ... #Diagnosis #Workup
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Prolonged PTT, Normal ... Prolonged PTT, Normal ... #Differential #Diagnosis ... Algorithm #Causes #Hematology ... #coagulation #disorders
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
- Differential Diagnosis ... Destruction • Abnormal ... • Vasculitis Coagulation ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... vascular disorders, coagulation ... #Differential #Diagnosis ... #hematology #rheumatology
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential Diagnosis ... Algorithm Signs ... Reticulocytes • Abnormal ... #Differential #Diagnosis ... #Algorithm #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... consumption of coagulation ... Intravascular #Coagulation ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
bruising • Skin ... type 2B) • Normal ... PT/INR • Normal ... VonWillebrand #Disease #Diagnosis ... #Hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
splenomegaly, abnormal ... neurology, back pain Haematology ... cell disease Rheumatology ... Pathway #Child #Peds ... #Pediatrics #Diagnosis
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
organ-specific signs ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation ... Thrombocytopenia - Normal ... - APTT < 1.5 x normal ... #diagnosis #causes ... treatment #management #hematology