36 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Coagulation Tests ... - Prolonged PT ... and Prolonged PT ... #Laboratory #Hematology ... #Diagnosis #Workup
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
(INR), Normal PTT ... Prolonged PTT, Normal ... #Differential #Diagnosis ... Algorithm #Causes #Hematology ... #coagulation #disorders
Coagulation Cascade Mnemonic - PITT vs PET
PITT (with an I) = Intrinsic = APTT
Coagulation Cascade ... E)= Extrinsic=PT ... @pinoygastro #Coagulation ... Mnemonic #PITT #PET #diagnosis ... #hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Intravascular Coagulation ... platelet aggregation PT ... using INR use PT ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
bruising • Skin ... type 2B) • Normal ... PT/INR • Normal ... VonWillebrand #Disease #Diagnosis ... #Hematology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Clotting tests can be abnormal ... PT and/or aPTT) ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
- Differential Diagnosis ... Destruction • Abnormal ... • Vasculitis Coagulation ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... Step 1: Is the PT ... Prolonging the PT ... APTT #prolonged #diagnosis ... #hematology #evaluation
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Jcortesizaguirr #Abnormal ... #Causes #diagnosis ... #differential #hematology ... #coagulation
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... antiglobulin test, PT ... hemosiderin • PT ... /aPTT normal • ... Management #Algorithm #hematology