7 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... Necrotizing myopathy ... Dermatomyositis ... can present with rash ... and anti-HMGCR myopathy
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Myositis and Myopathies ... Anti-Jo, +Anti-Mi2 Dermatomyositis ... muscle weakness, rash ... Inclusion Body Myositis ... , +Anti-dsDNA, Myositis
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Creatine Kinase - Causes ... Critical Illness Myopathy ... Subacute to Chronic Causes ... : dermatomyositis ... Inclusion body myositis
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Tetanus, Transverse Myelitis ... Mitochondrial myopathy ... , Polymyositis/dermatomyositis ... Neuromuscular #Weakness #Causes
Dermatomyositis
A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
Dermatomyositis ... This is a case of ... dermatomyositis ... 1) heliotrope rash ... usually indicates myopathy
Dermatomyositis with heliotrope rash, shawl sign, and Gottron's papules

A middle-aged man describes progressive difficulty combing his
Dermatomyositis ... with heliotrope rash ... out this is a case ... of dermatomyositis ... usually indicates myopathy
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... Symptoms: • Gottron rash ... INCLUSION BODY MYOSITIS ... syndrome • If myopathy ... statins - probably caused