71 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... constitutional symptoms ... Discontinuation of causal ... 40, F:M 9:1 • Clinical
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin Rash ... - Differential ... Bullous systemic lupus ... #dermatology #Differential ... Diagnosis #Algorithm #causes
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... (aPL) 30-45% Differential ... autoantibodies #signs #symptoms ... #mimickers #differential
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... hair follicles -> causes ... Phenomenon #Lupus ... diagnosis #signs #symptoms
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Joint Disorders - Differential ... with Systemic Lupus ... should have other symptoms ... like “butterfly rash ... Disorders #msk #Differential
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Autoimmune Vasculitis (lupus ... #Differential # ... Diagnosis #Algorithm #Causes
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... everywhere) 2) A rash ... the face (many differential ... pericarditis » is...lupus ... 6) An annular rash
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... , oral ulcers, Lupus ... Positive in 60-80% of cases
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
Visual or auditory symptoms ... conjunction with symptoms ... Inflammatory causes ... syndrome • Systemic lupus ... #inflammatory #differential
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Photosensitivity, Butterfly rash ... Thrombocytopenia #Lupus ... erythematosus #signs #symptoms