48 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... #Pharmacology #Pathophysiology ... Mechanisms #DOAC #Hematology
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
numerals refer to coagulation ... #Hemostasis #Pathophysiology ... #Coagulation #Cascade ... #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... • Vasculitis Coagulation ... deficiencies Coagulation ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... Diagnosis #Algorithm #Causes ... #Hematology #coagulation
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
vascular disorders, coagulation ... Platelet defects • Coagulation ... Kasabach-Merritt syndrome Coagulation ... Differential #Diagnosis #hematology ... #rheumatology #
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation ... protein C and S Pathophysiology ... Treat primary cause ... #diagnosis #causes ... treatment #management #hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... artery aneurysm: Causes ... intravascular coagulation ... Diagnosis #clots #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
presents with coagulation ... child * Severe cases ... pregnancy * Severe coagulation ... Obstetrics #OBGyn #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
presents with coagulation ... child * Severe cases ... pregnancy * Severe coagulation ... AFLP #obstetrics #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... : • Palpable Rash ... Complete blood count coagulation ... Diagnosis #Algorithm #Causes