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rheumatology lupus management neurology erythematosus systemic vasculitis autoimmune complications msk myositis rhabdomyolysis treatment algorithm als amyotrophic anaplasma arthritis autoantibodies biliary
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... Dermatomyositis ... , Shaw sign, holster ... sign, and Gottron's ... Can also see mechanics
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... Myopathy (Also caused ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Anaplasma Infection - Anaplasma phagocytophilum Pathophysiology: • Obligate, intracellular bacteria • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... within morulae Signs ... and symptoms: ... shaking chills • Rash ... Anaplasma #Infection #diagnosis
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... hair follicles -> causes ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... -> Heliotrope Rash ... Polymyositis #PM #Diagnosis ... #Pathophysiology ... #Signs #Symptoms
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
69% - Malar rash ... Lupusreference #SLE ... autoantibodies #signs ... #symptoms #mimickers ... #differential #
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Diagnosis and Management ... Immobilization, Crush ... (polymyositis/Dermatomyositis ... ) AKI - Pathophysiology ... #Summary #causes
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework High Altitude Pulmonary Edema: • Accumulation
Edema (NCPE) - Differential ... Diagnosis Framework ... • Signs/Symptoms ... • Signs/Symptoms ... diagnosis #NCPE
Non-Infective Endocarditis (NBTE / Marantic Endocarditis) Non-infective endocarditis is also known as: Non-bacterial thrombotic endocarditis (NBTE), Aseptic
patients with SLE ... absent How can we differentiate ... pathognomonic signs ... /symptoms or echo ... #pathophysiology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... Management Summary Causes ... Immobilization - Crush ... : Polymyositis/Dermatomyositis
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