43 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
common in SLE, autoimmune ... c-ANCA - Vasculitis ... - Vasculitis, e.g ... #diagnosis #table ... #rheumatology #
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Diagnosis Algorithm ... HUS • DIC • Vasculitis ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Diagnosis Algorithm ... • Steroids • Vasculitis ... #Diagnosis #Algorithm ... #Causes #Hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... Diagnosis Framework ... Differential ... differential #diagnosis ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm ... #rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Diagnosis Framework ... • ANCA Associated ... : • Behcet Disease ... #rheumatology # ... differential #diagnosis
Diagnosis and management of Polyarteritis Nodosa (PAN)

Chapel Hill 2012 definition: 
Necrotizing vasculitis ofmedium or small arteries
Diagnosis and management ... associated with ANCA ... PolyarteritisNodosa #Rheumatology ... #Diagnosis #Management ... #Vasculitis #Differential
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated ... Vasculitis There ... #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... Diagnosis Framework ... Nodosa (PAN), ANCA ... associated vasculitis ... #Diagnosis #rheumatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... Cryoglobulinemia (MIXED) • ANCA ... #Diagnosis #hematology ... #rheumatology #