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differential acute hematuria renal workup aki blood glomerular nephritic nephritis syndrome syndromes urology atlas classification comparison diseases glomerulonephritis indications injury
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
hematuria and/or proteinuria ... casts or dysmorphic ... RBCs in urine)? ... Syndrome #Comparison #Algorithm ... #Nephrology #Diagnosis
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE) SLE patient develops
urine sediment ... , RBC casts, WBC ... casts) especially ... #diagnosis #algorithm ... #sle #nephrology
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
casts, eosinophiluria ... , granular casts ... /RTE; blend sediment ... #AIN #Algorithm ... #nephrology #diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
RBC casts in urine ... Proteinuria often ... severe cases ... may be in nephrotic ... #Nephrology #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... sediment - WBC/ ... RBC casts ... #Nephrology #Differential ... #Diagnosis #Algorithm
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
blood cells on urine ... microscopy. ... and/or RBC casts ... range) proteinuria ... #Algorithm #Causes
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... ) • Granular Casts ... • RBC Casts - ... #Urine #Microscopy ... #diagnosis
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
unilateral flank pain ... glomerular bleeding (proteinuria ... , RBC casts, dysmorphic ... for renal biopsy ... if cause not identified
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
sediment Microscopic ... sediment by microscopy ... casts → Diagnostic ... - Proteinuria ... #nephrology #renal
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... casts are seen ... 34t5DgJ #Urinary #Casts ... #Diagnosis #Nephrology
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