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differential aki hematuria workup blood glomerular kidneyinjury nephritis renal syndrome urology biopsy classification comparison diseases glomerulonephritis indications injury interpretation interstitial
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
hematuria and/or proteinuria ... casts or dysmorphic ... RBCs in urine)? ... Syndrome #Comparison #Algorithm ... #Nephrology #Diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... RBC casts in urine ... severe cases ... may be in nephrotic ... #Nephrology #Diagnosis
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Nephritis When ... , granular casts ... #Interstitial #Nephritis ... #AIN #Algorithm ... #nephrology #diagnosis
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE) SLE patient develops
Lupus Nephritis ... urine sediment ... , RBC casts, WBC ... casts) especially ... #diagnosis #algorithm
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
blood cells on urine ... and/or RBC casts ... • Hereditary nephritis ... and >3.5g/day (nephrotic ... #Algorithm #Causes
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic ... ) • Granular Casts ... • RBC Casts - ... #Urine #Microscopy
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... sediment - WBC/ ... RBC casts ... #Nephrology #Differential ... #Diagnosis #Algorithm
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... in acute tubular ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic ... #Diagnosis #Nephrology
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • Red cell casts ... renal disease • Granular ... #Microscopy #Atlas ... #nephrology #casts
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
repeat testing • Acute ... unilateral flank pain ... glomerular bleeding (proteinuria ... , RBC casts, dysmorphic ... if cause not identified
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