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RBC Casts on Urine Microscopy

Dr. Telma Lemos @TELMALEMOS10

#RBC #Casts #Urine #Microscopy #clinical #nephrology
RBC Casts on Urine ... Microscopy Dr. ... TELMALEMOS10 #RBC ... #Casts #Urine # ... #nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... • RBC Casts - ... #Urine #Microscopy ... #nephrology #interpretation ... #diagnosis
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
cases are caused ... IMPROVEMENT If the urine ... Assess UA w/ microscopy ... for WBCs, RBCs, ... casts, crystals
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
casts, eosinophiluria ... , microscopic hematuria ... proteinuria, granular casts ... AIN #Algorithm #nephrology ... #diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... RBC casts ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology ... #Algorithm #Causes
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... Hematuria: 3 or more RBC ... hematuria: - RBC ... castsDiagnostic ... #nephrology #renal
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup and Diagnosis ... casts, dysmorphic ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... if cause not identified
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
glomerular hematuria (RBC ... casts or dysmorphic ... RBCs in urine)? ... Comparison #Algorithm #Nephrology ... #Diagnosis
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • Red cell casts ... • White cell casts ... disease • Granular casts ... #nephrology #casts
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- BMP, cap, CBC ... - Urinalysis/microscopy ... UOP/weights - Urine ... #Nephrology #Diagnosis ... #Algorithm #Causes