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sle erythematosus algorithm ana antinuclear classification arthritis neurology oncology patterns testing treatment workup anemia antibodies diseases extravascular hemolysis hemolytic intravascular
Thrombotic Microangiopathies In Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Lupus Erythematosus ... #SLE #hematology ... #rheumatology # ... differential #diagnosis ... #causes
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... 2) LOOK FOR a cause ... → Systematic screening ... #management #treatment ... #rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Diagnosis Algorithm ... Lupus Erythematosus ... (Pancytopenia, WBC ... #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Inflammatory and Autoimmune ... Diseases: • Systemic ... lupus erythematosus ... hemoglobinuria • Antibody-mediated ... #Diagnosis #Hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
Classification Criteria for Systemic ... pericarditis • Hematologic ... Thrombocytopenia, Autoimmune ... Criteria #SLE #Systemic ... #diagnosis #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Atypical HUS, autoimmune ... Lupus Erythematosus ... #differential # ... hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
or Anti-NucIear Antibody ... Positive ANA ≠ Autoimmune ... Thyroid, Autoimmune ... ANA #patterns #rheumatology ... #diagnosis #differential
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential ... Diagnosis Algorithm ... Inflammatory • Systemic ... Lupus Erythematosus ... #Causes #Hematology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
an underlying autoimmune ... Inflammatory causes ... encephalomyelitis • MOG antibody-associated ... lupus erythematosus ... #inflammatory #differential
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
antibodies) • Systemic ... lupus erythematosus ... drug-induced SLE) • Systemic ... Antineutrophil #antibodies #diagnosis ... #rheumatology #
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