75 results
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Volume (MCV) - Differential ... Polychromatic Macrocytes, RBC ... Spherocytes, RBC ... #Hematology
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential ... • Extrinsic RBC ... • Intrinsic RBC ... #Anemias #Differential ... Diagnosis #Algorithm #hematology
Pathophysiology of Hemolytic Anemia
 - Defects in RBC internal contents (thalassemia, hemoglobinopathies, and metabolic defects)
 -
Pathophysiology of Hemolytic ... - Defects in RBC ... - Defects in RBC ... Pathophysiology #Hemolytic ... #Anemia #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... - Differential ... elliptocytosis - RBC ... Extravascular #Differential ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Decreased RBC ... Thalassemia • RBC ... Disorder • RBC ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... • Intrinsic RBC ... Extravascular #Causes ... #differential # ... diagnosis #hematology
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Red Blood Cell (RBC ... cell, Other RBC ... Howell-Jolly bodies #RBC ... Microscopy #Pathology #Hematology ... #Dyspmorphic #BloodSmear
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... 2) External (RBC ... 3) Internal (RBC ... #Differential # ... Diagnosis #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... ↑ LDH • Anti-RBC ... • Blood smear: Differential ... 2) LOOK FOR a cause ... management #treatment #rheumatology
Common RBC Inclusions and Associations
 • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia
 • Heinz
Common RBC Inclusions ... Asplenism, Severe hemolytic ... Sideroblastic anemia, Hemolytic ... Sickle cell, MDS #RBC ... Bodies #diagnosis #hematology