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differential algorithm management causes workup leukemia syndrome systemic chronic cll disorders generalized hemolytic lymphocytic mds monoclonal myelodysplastic pruritus secondary thrombocytosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Artifact (redo CBC ... effect following treatment ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
- Differential Diagnosis ... Lymphocytic Leukemia (CBC ... #Differential #Diagnosis ... Algorithm #Causes #Hematology ... #Oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC ... Blood #Disorders #hematology ... #Differential #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... cytopenias (usually anemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Neutrophils - Low RBC ... Disease • Parasites ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
on the left Myeloblast ... Differential Diagnosis ... counts may delay diagnosis ... #differential #diagnosis ... #CBC #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... Vmphocytosis on routine CBC ... 5) Symptoms of anemia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Rheumatologic, Vasculitides ... #Algorithm #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... cardiac valve, vasculitis ... #Differential #Diagnosis ... Algorithm #workup #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... decreased PLT count: CBC ... changes), high MCV anemia ... #Differential #Diagnosis ... Causes #Workup #hematology
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