12 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
RBC casts in urine ... severe cases ... #Classification ... #Proteinuria #Nephrology ... #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
hematuria (RBC casts ... urine)? ... #Syndrome #Comparison ... #Algorithm #Nephrology ... #Diagnosis
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
sterile pyuria, WBC casts ... , granular casts ... #Nephritis #AIN ... #Algorithm #nephrology ... #diagnosis
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... edgarvlermamd - Nephrology ... #Diagnosis #Nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic ... #Urine #Microscopy ... #nephrology #interpretation ... #diagnosis
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... • Red cell casts ... • White cell casts ... • Hyaline casts ... #nephrology #casts
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
, RBC casts, dysmorphic ... → Refer to Nephrology ... for renal biopsy ... cystoscopy • Refer to Nephrology ... #blood #urine
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
hematuria: - RBC casts ... - Proteinuria ... #causes #urology ... #nephrology #renal ... #urine #blood
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Epithelial cell casts ... polyangiitis /microscopic ... Nephritis • Drugs ... #AKI #Acute #KidneyInjury ... #Nephrology #Differential
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... microscopy / urinary ... osmolarity If cause ... Interstitial nephritis ... #nephrology #causes