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Map of proliferative blood disorders. 

By Ariella Coler-Reilly @ariellastudies

#Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
blood #disorders #leukemia ... #hematology #oncology ... #diagnosis #CML ... #CLL #AML #Map
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Neutrophils • Immature/Myeloblasts ... CLL -> Invade Skin ... #Hematology #Oncology ... #Diagnosis
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
Causes of Diffuse ... - Differential Diagnosis ... • Neoplastic (Leukemia ... Metastatic) #Diffuse ... Algorithm #Causes #Hematology
Leukemic skin Infiltrate: Patient with known Acute Myelogenous Leukemia presented with diffuse
bullous lesions (not shown). These
Leukemic skin Infiltrate ... Acute Myelogenous Leukemia ... presented with diffuse ... Clinical #Photo #Dermatology ... #Infiltrate #AML
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse ... - Differential Diagnosis ... Hodgkin's Lymphoma #Diffuse ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Chronic Myelogenous Leukemia ... effect following treatment ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... transformation to acute leukemia ... only curative treatment ... #Management #treatment ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
- Differential Diagnosis ... Chronic myeloid leukemia ... (CML) - Dr. ... #Differential #Diagnosis ... #Causes #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Symptomatic anemia Diagnosis ... megaloblastic anemia Treatment ... to MDS or acute leukemia ... #management #treatment ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... lymphadenopathy more diffuse ... Treated Like Acute Leukemias ... relapse - Amy ... pathophysiology #Hematology