21 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic ... Leukemia, Tumour ... • TTP/HUS • DIC ... Algorithm #Causes #Hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... megaloblastic anemia Treatment ... to MDS or acute leukemia ... Anemia #diagnosis #management ... #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... dys- (abnormal) -plastic ... transformation to acute leukemia ... only curative treatment ... #treatment #hematology
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
- Malignancy: Leukemia ... Gangrenosum, NEH T - Treatment ... Purpura fulminans/DIC ... dermatoses #skin ... MINTC #Mnemonic #dermatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Post-partum • Acute DIC ... promyelocytic leukemia ... Summary #table #comparison ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... Neutrophils • Immature/Myeloblasts ... Fibrinolysis & DIC ... CLL -> Invade Skin ... #Hematology #Oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... virus (EBV) • Leukemia ... anemia Treatment ... Anemia #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Hepatomegaly • Skin ... Pure red cell aplasia ... microglobulin Treatment ... workup #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Intravascular Coagulation (DIC ... promyelocytic leukemia ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... MAS, Visceral, DIC ... Disease #diagnosis #management ... #treatment #rheumatology