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differential aflp pregnancy anemia obgyn oncology table algorithm coagulation intravascular liver product reactions ttphus aplastic cirrhosis deficiencies deficiency disease disseminated
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Leukemia, Tumour ... Non-lmmune: • HELLP ... • TTP/HUS • DIC ... #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Thrombocytopenia ... schistocytes, DIC ... #AFLP #obstetrics ... #hematology #diagnosis ... #table #comparison
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Thrombocytopenia ... schistocytes, DIC ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... Microangiopathy: DIC ... - Pregnancy: HELLP ... #Framework #hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... Algorithm Blood ... purpura (TTP) • HELLP ... intravascular coagulation (DIC ... #Obstetrics #OBGyn
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... ABO incompatible blood ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Post-partum • Acute DIC ... Septic shock, Obstetric ... promyelocytic leukemia ... Summary #table #comparison ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Neutrophils • Immature/Myeloblasts ... infiltrates (anemia, thrombocytopenia ... Fibrinolysis & DIC ... #Hematology #Oncology ... #Diagnosis
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
DIC • Aminotransferases ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... intravascular coagulation (DIC ... ) - HELLP syndrome ... microangiopathy: Thrombotic thrombocytopenic ... #hematology #anemia
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