14 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Megakaryopoiesis • Aplastic ... Leukemia, Tumour ... #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... dys- (abnormal) -plastic ... old, ~10,000 new cases ... transformation to acute leukemia ... #hematology #oncology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... child * Severe cases ... @Bloodman #Thrombocytopenia ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... virus (EBV) • Leukemia ... #Anemia #oncology ... #hematology #diagnosis ... #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Neutrophils • Immature/Myeloblasts ... infiltrates (anemia, thrombocytopenia ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Neutropenia, anemia, thrombocytopenia ... Pure red cell aplasia ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... with anemia or thrombocytopenia ... #oncology #hematology ... #hemeonc #diagnosis ... #management
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... acid metabolism products ... = nonspecific (nausea ... #hepatology #obstetrics ... #obgyn #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology