30 results
diagnosis differential algorithm management lupus arthritis erythematosus hemolytic oncology testing approach extravascular hemolysis intravascular joint leukemia msk pain thrombocytopenia vasculitis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Algorithm Decreased WBCs ... RA, SLE, PRV, Chronic ... Diagnosis #Algorithm #Causes ... #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... ↑ LDH • Anti-RBC ... 2) LOOK FOR a cause ... → Systematic screening ... management #treatment #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... • ITP • SLE ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... test, ANA (e.g., SLE ... changes), high MCV anemia ... or if a primary hematologic ... #Workup #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... • Anemia of Chronic ... #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... genotypes): SS, SC, SE ... elliptocytosis, autoimmune ... Diagnosis #Algorithm #workup ... #hematology #testing
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis ... autoimmune disease ... pericarditis • Hepatic: PBC ... Scleroderma #SSc #rheumatology ... symptoms #testing #workup
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... Thrombocytopenia, Autoimmune ... #Criteria #SLE ... Erythematosus #diagnosis #rheumatology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
on the left Myeloblast ... Corticosteroid use • Autoimmune ... Even with normal WBC ... relative to both WBC ... #CBC #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... • Immunologic Workup ... Positive in 60-80% of cases ... #lupus #Systemic ... Management #Summary #rheumatology
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