20 results
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... 1 or Type 3) — differentiate ... Von Willebrand Disease ... #disorders #hematology ... #hemepath #differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... RBC's secondary to platelet ... Thrombocytopenia • Platelet ... : Platelet Defects ... #Differential #
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... / Bruising - Differential ... Sequestration Disordered ... Platelet Function ... Connective Tissue Disorders
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Thrombocytopenia and Platelet ... Disorders - Differential ... History: - Prior platelet ... Thrombocytopenia #Platelet ... #Disorders #Differential
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... disorder Clinical ... Laboratory • Normal platelet ... VonWillebrand #Disease ... #Diagnosis #Hematology
Platelet Disorders - Differential Diagnosis Framework

Qualitative Defects:
 • Adhesion
 • Aggregation
 • Secretion

Quantitative Defects:
 • Production:
Platelet Disorders ... - Differential ... ASanchez_PS #Platelet ... #Disorders #Differential ... #Diagnosis #hematology
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
in Children Platelet ... - Increased platelet ... Hypersplenism - Impaired platelet ... Drug-induced Platelet ... count normal - Platelet
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Hemostasis - Differential ... Qualitative defect in platelets ... characteristic of a platelet ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Petechiae • Purpura ... Hemorrhagic bullae • Purpura ... Findings in DIC: • Platelet ... Thrombocytopenia - Platelet ... • Severe Liver Disease
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Unstable hemoglobin disorders ... lymphoma, Multiple myeloma ... #Red #BloodCell ... RBC #Morphology #differential ... #diagnosis #hematology