10 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... Diagnosis Neurologic-Centered ... nemaline myopathy Cutaneous-centered ... Diagnosis #hematology ... #oncology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
patients with monoclonal ... concerning for myeloma ... #monoclonal #gammopathy ... algorithm #diagnosis ... #management #hematology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
tubulopathy • Monoclonal ... gammopathy of renal ... #Cancer #Oncology ... #Differential # ... Diagnosis #Classification
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... Summary Framework Hematologic ... to IgM multiple myeloma ... #Monoclonal #Gammopathy ... #diagnosis #oncology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Antibodies against myelin-associated ... glycoprotein (MAG) in myelin ... #Monoclonal #Gammopathy ... Complications #diagnosis ... #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
gangrenosum • Cutaneous ... et diutinum Neurologic ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Cutaneous manifestations associated with myelodysplastic syndrome
 • Myeloid hemopathy with the most frequent skin lesions (20%)
Cutaneous manifestations ... myelodysplastic syndrome • Myeloid ... myelodysplastic #syndrome #differential ... #diagnosis #dermatology ... #oncology #clinical
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
presentation) • Cutaneous ... Diagnosis Monoclonal ... gammopathy of undetermined ... significance (MGUS ... ), CLL, Myeloma
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
: • MGUS • Multiple ... myeloma • Waldenstrom ... Smoldering multiple myeloma ... Gap #ProteinGap #differential ... #diagnosis #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
vasculitis) • Cutaneous ... skin injury) • Neurologic ... Behcet disease) Differential ... refractory disease : monoclonal ... #management #signs