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diagnosis dermatology syndrome myelodysplastic treatment hepatology mds rash acne acromegaly aflp algorithm anemia aplastic apml arterial arteritis biliary cholangitis cirrhosis
Cutaneous manifestations associated with myelodysplastic syndrome • Myeloid hemopathy with the most frequent skin lesions (20%)
myelodysplastic syndrome • Myeloid ... most frequent skin ... myelodysplastic #syndrome #differential ... #oncology #clinical ... #skin
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... of germinative skin ... Causes: 1) Exfoliative ... #Diagnosis #Dermatology ... Nikolsky #Algorithm #Differential
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... Summary myelo ... old, ~10,000 new cases ... #treatment #hematology ... #oncology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Arterial Thrombosis - Differential ... Testosterone - Coumadin skin ... coagulation and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... infiltration) Differential ... Liver #Pregnancy #hepatology ... #pathophysiology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... POEMS (Sclerotic myeloma ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
CML (Chronic Myeloid ... -> AML: Blast crises ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
characterized by extensive skin ... Edema in 70% of cases ... Skin involvement ... Resolution > 15 days Differentials ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
, hair growth, skin ... tags, skin thickening ... malignancy Pathophysiology ... Differential Diagnosis ... or refractory cases
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