25 results
diagnosis differential management antibodies monoclonal workup algorithm anemia arthritis erythematosus leukemia lupus mds mgus myelodysplastic patterns rheumatoid systemic treatment acquired
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
alveolitis, ear and ... thromboembolic disease ... criteria for 1) hematologic ... cells NEJM Review ... Autoinflammatory #Somatic #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... SLE), Sjogren's Syndrome ... @AnnKumfer #Antinuclear ... #patterns #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... cases • Sjögren syndrome ... #Antinuclear #Antibody ... antibodies #diagnosis #rheumatology ... #diseases
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Erythematosus - Summary Antinuclear ... (ANA) - 95% - Initial ... block • Sjogren syndrome ... polymyositis overlap syndrome ... Summary #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... SLE), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... @AnnKumfer #Antinuclear ... #patterns #rheumatology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma ... ULN R - Renal disease ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
capillary leak syndrome ... • Schnitzler syndrome ... Ig deposition disease ... Differential #Diagnosis #hematology ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... Management Summary myelo ... Myelodysplastic #Syndrome ... Management #treatment #hematology ... #oncology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... lymphoma, multiple myeloma ... thrombocythemia), Autoimmune disease ... vonWillebrand #Syndrome ... Management #treatment #hematology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... Association with disease ... SLE-SSc-AlM overlap syndromes ... with auto-immune diseases ... erythematosus #diagnosis #rheumatology
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