66 results
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
symmetric muscle weakness ... symmetric muscle weakness ... Fever, No muscle weakness ... Proximal muscle weakness ... diagnosis #comparison #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... level of muscle weakness ... have significant weakness ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... Features of hematologic ... bleeding, fatigue/weakness ... Differential #Diagnosis #Algorithm ... #hematology #WBC
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
suspect underlying hematologic ... Diagnosis and Treatment ... Algorithm Matthew ... Syndrome #HES #Hematology ... diagnosis #management #algorithm
Causes of Peripheral Weakness - With and Without Sensory Changes - Differential Diagnosis Algorithm
With Sensory Changes:
of Peripheral Weakness ... Differential Diagnosis Algorithm ... • No Objective Weakness ... Oculomotor • Myopathy ... Differential #Diagnosis #Algorithm
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Differential Diagnosis Algorithm ... Non malignant hematologic ... effect following treatment ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Immune-Mediated Necrotizing Myopathy ... Myopathies #Idiopathic #Myopathy ... Comparison #Managment #algorithm ... #Rheumatology #
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
of Peripheral Weakness ... Differential Diagnosis Algorithm ... No Objective Weakness ... • Congenital Myopathy ... Differential #Diagnosis #Algorithm
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... any time during treatment ... symmetric muscle weakness ... after DC Statin Treatment ... diagnosis #management #treatment
Venous Thromboembolism Treatment Algorithm
Branch points: 
Active bleeding?  Active malignancy? Provoked?

- Dr. Joseph Shatzel
@Clotmaster

#Management #VTE #DVT
Thromboembolism Treatment ... Algorithm Branch ... Management #VTE #DVT #Algorithm ... Thromboembolism #Treatment ... #Hematology #Anticoagulation