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diagnosis differential neurology rheumatology cord endocrinology hypothyroid management signs sle spinal spinalcord systemic treatment algorithm autoimmune cauda caudaequina cerebritis classification
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... femoral heads • Myopathy ... (Also caused by ... #Erythematosus ... pathophysiology #signs #symptoms
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
proximal myalgia and weakness ... symmetric muscle weakness ... Guillain-Barré syndrome ... GBS), systemic lupus ... erythematosus (
Hypothyroidism – symptoms and signs. Symptoms: Tiredness/malaise, Weight gain, Anorexia, Cold intolerance, Poor memory, Change in appearance, Depression, Poor libido,
Symptoms: Tiredness ... Myalgia, Muscle weakness ... Carpal timel syndrome ... hypertrophy, Proximal myopathy ... #Diagnosis #PhysicalExam
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... Demyelinating Syndrome ... Aseptic Meningitis, Myelopathy ... autoantibodies that will cause ... #Erythematosus
Myoedema in Hypothyroidism on Physical Exam Hypothyroidism is a clinical syndrome resulting from the production, secretion or
is a clinical syndrome ... and scaly skin, myopathy ... Myopathy due to ... reflex hammer, caused ... Hypothyroidism #PhysicalExam
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 Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
findings: • Symptoms ... Non-compressive Spinal Cord Causes ... - Radiation myelopathy ... - Radiation myelopathy ... MCTD, Sjogren syndrome
Lesions of the Spinal cord - Spinal Cord Syndromes Spinal cord lesions can result in permanent neurologic
Causes of spinal ... • Extrinsic Causes ... Lower motor neuron symptoms ... Upper motor neuron symptoms ... - Radiation myelopathy
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... - Emergency Causes ... • HIV related myelopathy ... lower extremity weakness
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
NECROTIZING AUTOIMMUNE MYOPATHY ... • If myopathy ... statins - probably caused ... ANTI-MITOCHONDRIAL MYOPATHY ... Autoimmune #Myositis #Myopathy
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... myalgia and muscle weakness ... such as systemic lupus ... erythematosus, ... Presentation - Systemic Symptoms
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