18 results
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
• Inflammatory myopathy ... such as • Statin-induced ... myopathy (SAMS) ... Atorvastatin Diagnosis ... #diagnosis #management
Acute Coronary Syndrome (ACS) Definitions - Stable Angina, Unstable Angina, NSTEMI, STEMI
1 STABLE ANGINA - Angina
Acute Coronary Syndrome ... (ACS) Definitions ... - Stable Angina ... #Diagnosis #Cardiology ... #ACS #Unstable
ISCHEMIA Trial - Management Algorithm for patients with Stable Angina

Stress Test -> ? +moderate or severe
Angina Stress ... acute coronary syndrome ... (ACS) evaluation ... #Diagnosis #Management ... #Algorithm #Cardiology
Vasospastic (Prinzmetal) Angina
Definition / Epidemiology:
 • Rest angina attributed to coronary artery vasospasm.
 • Patients often
Vasospastic (Prinzmetal) Angina ... younger than other ACS ... troponin elevation Diagnosis ... tests in cath lab Treatment ... #cardiology #diagnosis
Beta Blockers - Pharmacology Comparison Table
Metoprolol:
 • Receptors: β1
 • Indications: Rate control of a-fib/a-flutter, Suppression
Suppression of PACs ... angina, Acute coronary ... syndrome, Post-MI ... angina, Essential ... #Receptors #cardiology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Myositis Necrotizing myopathy ... anti-synthetase syndrome ... /full triad at diagnosis ... and anti-HMGCR myopathy ... after 2 years of treatment
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Anti-Synthetase Syndrome ... Mediated Necrotizing Myopathy ... MSAs #clinical #diagnosis ... #rheumatology #table
Cardiorenal Syndrome (CRS) Types
 • Type 1 - Acute CRS: Alteration of renal perfusion is the
Cardiorenal Syndrome ... Type 3 - Acute RCS ... Hypertension, CKD induced myopathy ... #Cardiorenal #Syndrome ... #CRS #Types #cardiology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Motor Nerves: ALS ... Guillain-Barre syndrome ... Lambert Eaton Syndrome ... Mitochondrial myopathy ... #differential #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Aseptic Meningitis, Myelopathy ... permeability Diagnosis ... (for secondary APS ... #management #treatment