12 results
diagnosis rheumatology differential management algorithm anemia causes lupus monoclonal oncology sle acutephasereactants ana anca antibodies antibody antineutrophil antinuclear antinxp2 antinxp2dm
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... Renal Disease, Liver ... Myelodysplasia #Anemia #MCV ... Algorithm #Causes #Hematology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
dL the ULN R - Renal ... /dL or CC < 40 ml ... M spike: • CML ... lymphoproliferative diseases, CML ... MGUS #diagnosis #hematology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis Associated with : • Absence of skin
Renal involvement ... Mean eGFR - 39.5 mL ... /min • <60 mL/ ... TerrierBen #Renal ... Vasculitis #Management #Rheumatology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL ... probably < 1500ng/mL ... malabsorption) if < 200ng/mL ... Special cases (e.g. renal ... Measurement #SLE #rheumatology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Corpuscular Volume (MCV ... Reticulocytosis • Renal ... Algorithm #Causes #Hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
disease (panuveitis, retinal ... aseptic meningitis), MCC ... involvement (uveitis or retinal ... Ocular: Giant retinal ... signs #symptoms #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
scleroderma) - Anti-Scl ... polyangiitis without renal ... ANCA+ 30-60% • Renal-limited ... antibodies #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & MBL ... Evans • ITP • Cl-NH ... vascular beds-renal ... , retinal, DVT, ... Paraproteinemias #Hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
in non-muscle myosin ... cataracts, and renal ... differential #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Malignancy (e.g. hematologic ... APLA/LAC: • Renal ... vein thrombosis Hematologic ... La, anti-Jo-1, SCL ... Erythematosus #Diagnosis #Rheumatology
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