47 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... scleroderma) - Anti-Scl ... polyangiitis without renal ... #Antinuclear #Antibody ... antibodies #diagnosis #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Discoid Rash A Antinuclear ... Antibody (ANA) ... Arthritis R Renal ... erythematosus #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Erythematosus - Summary Antinuclear ... (ANA) - 95% - Initial ... severe disease & renal ... Summary #diagnosis #rheumatology ... #management
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... Smith, Sm/RNP, Scl ... ARUPConsult @ARUPLabs #ANA ... #Antinuclear #Antibody ... differential #diagnosis #rheumatology
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
Renal involvement ... Combined decr of C3 and ... TerrierBen #Renal ... Cryoglobulinemia #Vasculitis #Management ... #Rheumatology #
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL ... and probably < ... Special cases (e.g. renal ... Measurement #SLE #rheumatology ... levels #lupus #management
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
dL the ULN R - Renal ... /dL or CC < 40 ml ... M spike: • CML ... diseases, CML, ... MGUS #diagnosis #hematology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
aorta • Head and ... pancreas, biliary, renal ... autoantibodies (antinuclear ... Disease #diagnosis #management ... workup #treatment #rheumatology
Management of adult IgA Vasculitis (Henoch-Schönlein purpura) - Treatment algorithm for the management of IgAV patients
Management of adult ... algorithm for the management ... initial presentation and ... long-term outcome of renal ... #Treatment #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
disease (panuveitis, retinal ... involvement (uveitis or retinal ... Ocular: Giant retinal ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology