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Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency ... Labs: Ferritin, iron ... loss: GI bleed, GU ... Hemodialysis • Iron ... Algorithm #ferritin #hematology
Iron Panel Interpretation Iron deficiency - ↓ Iron, ↑-nl Transferrin / TIBC, ↓ Transferrin Saturation, ↓
Iron Panel Interpretation ... Iron deficiency ... - ↓ Iron, ↑-nl ... ↑-nl Ferritin Iron ... #differential #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Non malignant hematologic ... states • Non-hematologic ... malignancy • Iron ... Algorithm #Causes #Hematology
Iron Deficiency in Heart Failure - Diagnosis and Treatment Algorithm Diagnosis: Ferritin <100 ng/mL (absolute ID) OR
Iron Deficiency ... Ferritin <100 ng ... Ferritin 100-299 ng ... and Ill HF with iron ... deficiency, IV iron
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... absorption and iron ... Ferritin <100 ng ... Ferritin 100-299 ng ... Treatment - IV Iron
Iron Deficiency Anemia (IDA) Tests: • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Iron Deficiency ... TIBC - Amount of Iron ... of total body iron ... @DharSaty #Iron ... Fe #diagnosis #hematology
Iron Deficiency in Congestive Heart Failure (CHF) Iron deficiency (ID) in heart failure is a common comorbidity
Iron Deficiency ... Failure (CHF) Iron ... Ferritin < 100 ng ... Ferritin 100 - 299 ng ... x 2.4 + depot iron
Pathology - Hepatocyte Pigments Lipofuschin (H&E) Alpha-I-antitrypsin globules (PAS-D) Mallory's hyaline / Mallory Denk Bodies Giant Mitochondria
macrophage (PAS-D) Iron ... blue stain) Iron ... Pigments #Pathology #Hepatology
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
Causes of Iron Deficiency ... , ulcer, IBD), GU ... Hemodialysis • Iron ... Lactation, Low iron ... Decreased ferrous iron
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
decreased, serum iron ... MCV/RBC>13 • Iron ... increased, serum iron ... increased, Serum iron ... Algorithm #Causes #Hematology
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