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erythematosus hematology management sle systemic neurology algorithm anticoagulation aps arterial associations autoantibodies cerebritis classification cns criteria cryofibrinogenemia differential embolism eularacr
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Syndrome (APS) ... ): • Lupus anticoagulant ... of 1 clinical event ... present Treatment (EULAR ... #Syndrome #APS
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... , others (RNP, aPL ... antibodies) • Antiphospholipid ... Antibody Syndrome ... #diagnosis #associations
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus Clinical ... Immunologic domains: • Antiphospholipid ... Erythematosus #diagnosis ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... permeability Diagnosis ... (for secondary APS ... CNS #neurology #rheumatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... • Nephrotic Syndrome ... fibrillation - Left ventricular ... Malignancy - Antiphospholipid ... antibodies (APLS
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Erythematous, macular ... Differential Diagnosis ... Clinical Features ... #Rheumatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid ... Syndrome (APLS) ... - 1 or more clinical ... excluded Testing: • Lupus ... Workup #Algorithm #diagnosis
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Ocular- 50%: Ptosis ... Generalized fatigue - ALS ... myasthenia Diagnosis ... Bedside: ice pack ... Myasthenia #Gravis #diagnosis
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
pulmonary emboli, and ocular ... : • + Clinical ... HUS and HIT • Antiphospholipid ... syndrome • Warfarin-induced ... #rheumatology #
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