8 results
SPICE (SPACE) Organisms
 - Colloquial acronym for gram-negative bacteria that have inducible, chromosomal beta-lactamase genes known
acronym for gram-negative ... bacteria that have ... genes known as AmpC ... #Diagnosis #Microbiology ... #Antibiotics
SPICE (SPACE) Organisms

Gram-negative bacteria that have inducible, chromosomal beta-lactamase genes known as AmpC - Resistance may
Gram-negative ... bacteria that have ... genes known as AmpC ... #Diagnosis #Microbiology ... #Antibiotics
HECK YES - Mnemonic for Organisms with AmpC Resistance

H	Hafnia alvei
E	Enterobacter cloacae
C	Citrobacter freundii
K	Klebsiella aerogenes
Yes	Yersinia enterocolitica

Formerly SPICE /
Gram-negative bacteria ... to beta-lactam antibiotics ... #HECKYES #SPICE ... #SPACE #Bacteria ... #Diagnosis #Microbiology
Streptocccus Pneumoniae
Microbiology: Gram Positive, Alpha-hemolytic, Catalase Negative
Epidemiology - 10% adult carriers:
 • Most common cause of:
Streptocccus Pneumoniae Microbiology ... Alpha-hemolytic, Catalase Negative ... peritonitis, and endocarditis ... Specificity of 97%) Treatment ... #diagnosis #management
Spinal Epidural Abscess - Illness Script
Epidemiology:
 - Patients at risk for bacteremia: IVDU, dental abscess, HD
Patients at risk for bacteremia ... , HD catheter, endocarditis ... Alcoholism, DM, HIV Microbiology ... imaging as needed Treatment ... Abscess #diagnosis #management
Candidemia Workup and Management - IDSA Guidelines
1) Antibiotics
 • Empiric: Echinocandins (e.g. micafungin) for most patients
Guidelines 1) Antibiotics ... Susceptibilities, Negative ... clinical concern for endocarditis ... Consider: Spine, ... #candidiasis #treatment
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Hypercoagulable (APLAS) Microbiology ... • Coagulase-negative ... • IV Antibiotics ... • Persistent bacteremia ... #diagnosis #management
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Hypercoagulable (APLAS) Microbiology ... aureus, Coagulase-negative ... hematuria, + RF Treatment ... • IV antibiotics ... • Persistent bacteremia