32 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... Mechanism: Lipopeptide antibiotic ... No gram negative ... MRSA bacteremia/endocarditis ... #Pharmacology #Antibiotics
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures
 - Did they receive antibiotics prior
with Infective Endocarditis ... (IE) Has Negative ... Did they receive antibiotics ... Decreased yield due to antibiotic ... #Infective #Endocarditis
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... . aerobic Gram negatives ... : serious gram negative ... effect (mainly in endocarditis ... #Pharmacology #Antibiotics
Infective endocarditis - etiology and sources of infection. 
 • Native and prosthetic 
valve endocarditis
 •
Infective endocarditis ... • Native and ... prosthetic valve endocarditis ... for TPN) and antibiotic ... #Infective #Endocarditis
Aortic and Mitral Valve Vegetations in Endocarditis on POCUS - PLAX

Why would this 30 y/o male
Vegetations in Endocarditis ... on POCUS - PLAX ... murmur... but with #POCUS ... mitral valves and pulmonary ... #Vegetations #Endocarditis
Complications of Staph Aureus Bacteremia
 • CNS Infections
 • Septic pulmonary embolism (0.9% - 18.8%)
 •
Infections • Septic pulmonary ... ) • Infective endocarditis ... - Native valve ... arthritis - Native
Endocarditis checklist
Initial evaluation
 • Peripheral blood cultures (three sets at three different sites)
 • Additional culture
Endocarditis checklist ... suspect right-sided endocarditis ... w/ septic pulmonary ... course • Adjust antibiotics ... Critical Care #Endocarditis
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Cryoglobulinemia, Endocarditis ... With associated pulmonary ... Pauci-immune mediated (Negative
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Endocarditis Summary ... • Coagulase-negative ... Cerebral > Splenic, pulmonary ... • IV Antibiotics ... #Endocarditis
Candidemia Workup and Management - IDSA Guidelines
1) Antibiotics
 • Empiric: Echinocandins (e.g. micafungin) for most patients
Guidelines 1) Antibiotics ... Susceptibilities, Negative ... clinical concern for endocarditis