19 results
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
) Diagnosis of ... condition (vs. secondary ... is diagnosed, in ... Thrombocytopenic #Purpura #management ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... leakage of RBC's secondary ... • Secondary Causes ... #Differential #Diagnosis ... #hematology #rheumatology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
almost) all TMAs cause ... are primary and secondary ... TMA is due to TTP ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Pregnancy - TTP ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
child * Severe cases ... of child 3) TTP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
levels >1g/L • Negative ... causes of secondary ... Cryoglobulinemia • TTP ... #rheumatology # ... hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... activity is the diagnostic ... antiglobulin tests - Negative ... impairment #TTP ... #Workup #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... APS), Secondary ... #rheumatology # ... cerebritis #diagnosis ... #management #treatment
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• TMA’s (HUS/TTP ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
pANCA anti-MPO - Negative ... Usual therapeutic management ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management