59 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... pANCA anti-MPO - Negative ... #comparison #table ... #rheumatology # ... diagnosis #management
Signs and Symptoms of Toxidromes

Sympathomimetic / GABAergic withdrawal 
Cholinergic 
Anticholinergic 
Opioid withdrawal 
Neuroleptic malignant syndrome 
Serotonin
Signs and Symptoms ... Serotonin syndrome ... #Toxidromes #Comparison ... #Table #Anticholinergics ... Sympathomimetics #Diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... Oral aphthae : SLE ... • Arthritis: SLE ... #signs #symptoms ... #rheumatology #
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... • CNS symptoms ... CTA • Liver lesions ... values supporting hematologic ... #diagnosis
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... • Immunologic Workup ... : - ANA > ... pANCA anti-MPO - Negative ... Erythematosus #Diagnosis
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... rheumatoid arthritis SLE ... LungDisease #CTILD #Diagnosis ... #Differential #Comparison ... #Table #Pulmonary
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... #diagnosis #associations ... #table
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE ... Cranial nerve lesions ... Demyelinating syndromes ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
toxidrome is a syndrome ... (set of symptoms ... antihistamines #Diagnosis ... Toxicology #Toxidromes #Comparison ... #Table #Anticholinergics