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diagnosis hematology causes algorithm clinical hemolytic nephrology video anemia hemolysis afferent management pupillary rapd relative autoimmune defects extravascular inherited intravascular
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
) - Differential ... Diagnosis Table ... (7-8%) DAT-negative ... #Differential # ... #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis - Differential ... Abnormal Hgb & Hgb Defects ... Hgb - Membrane Defects ... Extravascular #Differential ... Algorithm #Causes #Hematology
Relative Afferent Pupillary Defect Dr. Felipe Duarte Augusto @semiologianeurologica #RAPD #Relative #Afferent #Pupillary #Defect #Neurology #Clinical #Video #Pupils
Relative Afferent ... Pupillary Defect ... Afferent #Pupillary #Defect ... #Neurology #Clinical ... Video #Pupils #PhysicalExam
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 Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Autoimmune: Warm AIHA ... , Cold AIHA, Transfusion ... #Hemolysis #Differential ... #Diagnosis #hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias - Differential ... Hemolytic Anemias (AIHAs ... : Membrane defects ... Hemolytic #Anemias #Differential ... Diagnosis #Algorithm #hematology
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
Hemolysis DAT Negative ... ), C3d ( - ) WAIHA ... BrighamChiefs #direct ... Autoimmune #Hemolysis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
- Autoimmune (AIHA ... - Autoimmune (AIHA ... Intrinsic RBC Defects ... Extravascular #Causes #differential ... #diagnosis #hematology
Relative Afferent Pupillary Defect This maneuver of intermittent light stimulus is called the alternating light test or
Pupillary Defect ... afferent pupillary defect ... Afferent #Pupillary #Defect ... #Neurology #Clinical ... Pupils #MacrusGunn #PhysicalExam
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 Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... • Membrane defects ... Hypersplenism • AIHA ... Hemolytic #Anemia #Differential ... classification #hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Qualitative Platelet Defects ... Thrombasthenia • Defect ... #comparison #table ... #differential # ... diagnosis #hematology
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