109 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... With associated pulmonary ... involvement: Anti-GBM Disease ... Pauci-immune mediated (Negative
ILD of Known Cause - Differential Diagnosis
Exposure:
 • Occupational: Asbestosis, Silicosis, Hypersensitivity, Pneumonitis
 • Treatment Related:
ILD of Known Cause ... Pneumonitis • Treatment ... Connective Tissue Disease ... BrighamChiefs #ILD #Causes ... #pulmonary
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Framework NCPE Pathophysiology ... Causes include: ... acute cardiac disease ... • Normal or negative ... pg/ml EKG: • Negative
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Diagnosis Algorithm Relative ... Cyanosis without Pulmonary ... Apnea • Chronic Pulmonary ... #Hematology
Rapidly Growing Mycobacterial Infections

 • Mycobacterium abscessus - Is the most pathogenic and the most likely
most likely to cause ... pulmonary infection ... underlying lung disease ... It can also cause ... #differential #infectiousdiseases
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... autoinflammatory diseases ... hepatitis • Pulmonary ... diagnosis #management #treatment ... #rheumatology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
ULN R - Renal disease ... Causes of false- ... negative SPEP: ... amyloidosis Other causes ... MGUS #diagnosis #hematology
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Causes of Culture ... Negative Abscess ... antibiotics as a cause ... Autoimmune: Crohn's disease ... Differential #Diagnosis #InfectiousDiseases
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... by case) • Surgery ... #Syndrome #Treatment ... #pharmacology #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... disorders • Celiac disease ... effect following treatment ... Diagnosis #Algorithm #Causes ... #Hematology