31 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... old, ~10,000 new cases ... only curative treatment ... #Management #treatment ... #hematology #oncology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... causes differentiated ... Pauci-immune mediated (Negative ... #differential #diagnosis ... #algorithm #rheumatology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Causes of false- ... negative SPEP: ... amyloidosis Other causes ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Traditionally, congestive heart failure has been classified according to severity of symptoms, first formulated by the
sometimes advanced treatment ... flare ups that cause ... #Diagnosis #Cardiology ... HeartFailure #Staging #Classification ... #Stages #Classes
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Heart Failure Pathophysiology ... → Inflammation causes ... functional ID) Treatment ... endpoint of all-cause ... #management #cardiology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... Positive in 60-80% of cases ... pANCA anti-MPO - Negative ... life-threatening • Treatment ... Management #Summary #rheumatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Responsive to Treatment ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #Hematology #Diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis
In order to better classify heart failure, the American College of Cardiology Foundation and the American
American College of Cardiology ... With treatment, ... patients with a diagnosis ... #Diagnosis #Cardiology ... #Stages #Classes
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... contraction force (negative ... #Pharmacology #Classification ... #Classes #pathophysiology ... #cardiology