34 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... • Immunologic Workup ... pANCA anti-MPO - Negative ... Evolution: Chronic disease ... #Management #Summary
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... #Systemic #Lupus ... #diagnosis #rheumatology ... #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... Orange or Hep C Clinical ... cells can indicate disease ... #workup #oncology ... #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... to 1:1 F:M • Clinical ... pANCA anti-MPO - Negative ... Evolution: Chronic disease ... #diagnosis #management
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
Summary Clinical ... necrosis, Lyme disease ... viral arthritis Workup ... staphylococcus, gram negative ... #Management #Summary
Disseminated Gonococcal Infection - Diagnosis and Management Summary

Bacteremic spread of the Gram-negative diplococci Neisseria gonorrhoeae. History
and Management ... Summary Bacteremic ... spread of the Gram-negative ... typically part of the workup ... Purulent Arthritis Syndrome
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Cerebrovascular Disease ... permeability Diagnosis ... #management #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Malignancy (e.g. hematologic ... Clinical Features ... Erythematosus #Diagnosis
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
-15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... Negative association ... erythematosus #diagnosis ... #rheumatology #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Systemic lupus ... Clinical Presentation ... SJIA], systemic lupus ... #Diagnosis #Management ... #Hematology #Rheumatology