88 results
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
C3 positive or negative ... mediated - DAT: IgG negative ... Pathophysiology #diagnosis ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... workup, including BM ... #Differential #Diagnosis ... #Algorithm #hematology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
to Kidney: Anti-GBM ... involvement: Anti-GBM ... Pauci-immune mediated (Negative ... #differential #diagnosis ... #algorithm #rheumatology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
- Differential Diagnosis ... AIHA (7-8%) DAT-negative ... #Differential #Diagnosis ... #Table #hematology
Rheumatoid Arthritis - 2020 ACR-EULAR Classification
≥ 6 of 10 points = definite RA
Joint Involvement:
Arthritis - 2020 ACR-EULAR ... at least 1): Negative ... RF, negative anti ... Rheumatoid #Arthritis #diagnosis ... #rheumatology
Expected DAT Results in Autoimmune Hemolysis
DAT Negative Hemolysis
 • DAT Poly ( - ), IgG (
Hemolysis DAT Negative ... Autoimmune #Hemolysis #hematology ... #diagnosis
Algorithm for the Evaluation and Management of Transfusion Reactions

This algorithm was developed by Dr. Eric Madden,
at McGovern Med EM ... Reactions #Algorithm #Diagnosis ... #Management #Hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... Coxsackie, CMV, EBV ... • Ocular: uveitis ... Stills #Disease #diagnosis ... management #treatment #rheumatology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... normal • DAT negative ... #Differential #Diagnosis ... Management #Algorithm #hematology
Point-of-care Ultrasound for Diagnosis of Abscess in Skin and Soft Tissue Infections

1. POCUS is more accurate
Ultrasound for Diagnosis ... POCUS is more accurate ... POCUS has a negative ... LikelihoodRatios #Accuracy #Diagnosis ... VisualAbstract #EBM