17 results
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Acting on the Nephron ... - Diuretics and ... HCTZ) 5) Potassium-sparing ... spironolactone) #Pathophysiology ... #Nephrology #Nephron
Mechanisms of Loop Diuretic Action and Resistance. Panel A, loop diuretics circulate bound to protein. As
Mechanisms of Loop Diuretic ... Panel A, loop diuretics ... binding to sodium–potassium–chloride ... #Pathophysiology ... #Nephro #IM #LoopDiuretic
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... Piretanide Potassium ... loss through the nephron ... loop #thiazide #classes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... Post-hypercapnia • Diuretics ... differential #diagnosis #algorithm ... #potassium
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Loop and thiazide diuretics ... Differential #Diagnosis #Algorithm ... #causes #potassium
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
arteriole in the nephron ... dose salicylates, diuretics ... tubule in the nephron ... Release of purine bases ... Hyperuricemia #Pathophysiology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation Algorithm ... treated with IV potassium ... wasting from other causes ... suggests extra-renal causes ... Alkalosis: Emesis, Diuretics
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #high #pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... organic acids and bases ... acid and most diuretics ... vasopressin control #Nephron ... Segments #Function #Pathophysiology