44 results
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
arteriole in the nephron ... Tubular Poisons (Low ... dose salicylates, diuretics ... tubule in the nephron ... blood into the nephron
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... Metolazone Loop diuretics ... loss through the nephron ... loop #thiazide #classes
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis Algorithm ... Primary polydipsia, Low ... Helbert Rondon, MD @NephroMD ... #differential #algorithm ... #causes #nephrology
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
Mechanisms of nephron ... Reduced renal blood flow ... activities • Diuretic
Hypokalemia Differential Diagnosis Algorithm

Low intake 
• poor oral intake 

Renal loss 
• Medication 
• Hypomagnesemia 
•
Differential Diagnosis Algorithm ... Low intake ... Hypomagnesemia • Osmotic diuresis ... Differential #Diagnosis #Algorithm ... #Causes #Classification
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... Cl intake, Diuretics ... High Urine Cl-: Diuretics ... Differential #Diagnosis #Algorithm ... #Nephrology #Causes
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Loop and thiazide diuretics ... Post-obstructive diuresis ... Differential #Diagnosis #Low ... Magnesium #Table #Classification ... #Causes #Workup
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... organic acids and bases ... acid and most diuretics ... vasopressin control #Nephron
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Normal Acid-Base: Low ... Loop and thiazide diuretics ... Differential #Diagnosis #Algorithm ... #causes #potassium
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
symptoms (HA, nausea ... Diagnosis #EM #IM #Nephro ... #Differential #Algorithm