71 results
Renal tubular acidosis (RTA): refers to a group of conditions all of which cause the same
conditions all of which cause ... different types/causes ... Diagnosis #IM #Nephro ... RenalTubularAcidosis #Features #Table
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Thiazides diuretics ... Metolazone Loop diuretics ... loss through the nephron ... loop #thiazide #classes
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... organic acids and bases ... acid and most diuretics ... vasopressin control #Nephron ... Pathophysiology #Tubules #Table
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
arteriole in the nephron ... dose salicylates, diuretics ... tubule in the nephron ... blood into the nephron ... Release of purine bases
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Differential Diagnosis Algorithm ... , Diuretic excess ... Ketonuria, Osmotic diuresis ... #Causes #nephrology
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis Algorithm ... Helbert Rondon, MD @NephroMD ... #differential #algorithm ... #causes #nephrology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Excessive GI losses ... Loop and thiazide diuretics ... Post-obstructive diuresis ... Low #Magnesium #Table ... Classification #Causes
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Causes of High-anion ... Metabolic Acidosis Causes ... and chronic) Causes ... Generalized distal nephron ... differential #diagnosis #causes
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Differential Diagnosis Algorithm ... especially thiazide diuretics ... Differential #Diagnosis #Algorithm ... #Causes
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
symptoms (HA, nausea ... Diagnosis #EM #IM #Nephro ... #Differential #Algorithm