10 results
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... the collecting duct ... loss through the nephron ... the collecting duct ... #thiazide #classes
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... acid and most diuretics ... limb of Henle's loop ... limb of Henle's loop ... Segments #Function #Pathophysiology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Normal Acid-Base: Low ... • HTN Absent: Loop ... and thiazide diuretics ... Differential #Diagnosis #Algorithm
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Differential Diagnosis Algorithm ... tubular transport • Diuretics ... (loop/thiazide) ... aldosteronism Low ... Differential #Diagnosis #Algorithm
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Differential Diagnosis Algorithm ... Urine Mg > 10g • Loop ... Diuretics • Hypercalcemia-PTH ... Hypomagnesemia #Magnesium #Low ... #Diagnosis #Algorithm
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... Remote use of loop ... or thiazide diuretics ... - Normal/low ... #causes #urinary
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... Remote use of loop ... or thiazide diuretics ... alkalosis • Normal/low ... the indicated causes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Decreased intake (rare cause in isolation)
GI loss - Urine loss
Differential Diagnosis Algorithm ... contracted • Loop ... diuretics / Bartter's ... syndrome • Thiazide diuretics ... Differential #Diagnosis #Algorithm
Treatment algorithm for malignancy-associated hypercalcemia.
Hypercalcemia
 - Renal Failure → Dialysis with low Ca++ bath
Aggressive IV hydration
Treatment algorithm ... Dialysis with low ... Volume Overload → Loop ... diuretic IV Bisphosphonate ... Calcitonin Refractory Cases
Algorithm for Diagnosis and Management of Resistant Hypertension in CKD
Pseudoresistant Hypertension - Reduce barriers to adherence:
Algorithm for Diagnosis ... Modifications • Low ... Consider other causes ... Add loop diuretic ... Hypertension #CKD #Algorithm