16 results
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... modify immune function ... distal component of Nephron ... : CHF, HTN, Edema ... decreased renal blood flow
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... Vomiting, NGT suction ... Diuretics (late ... High Urine Cl-: Diuretics ... #Nephrology #Causes
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... and their Functions ... organic acids and bases ... acid and most diuretics ... #Pathophysiology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
anemia) • G-CSF ... GI losses (NG suction ... vomiting) • Low ... • Discontinued diuretic ... #nephrology #low
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... Intake: • Low ... RENAL LOSS: - Diuresis ... Differential #Diagnosis #Algorithm ... #Pathophysiology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
arteriole in the nephron ... Tubular Poisons (Low ... dose salicylates, diuretics ... Release of purine bases ... Hyperuricemia #Pathophysiology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic ... Differential Diagnosis Algorithm ... Vomiting • NG suction ... tubular transport • Diuretics ... #Causes
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Differential Diagnosis Algorithm ... loop or thiazide diuretics ... Vomiting/nasogastric suction ... - Normal/low ... #causes #urinary
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... Differential Diagnosis Algorithm ... through distal nephron ... EABV (e.g., CHF ... #Causes
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
lost via osmotic diuresis ... out of cells may cause ... has good renal function ... produces them when low ... DiabeticKetoacidosis #DKA #pathophysiology