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diagnosis management oncology hemeonc myelodysplastic rheumatology activation anemia aplastic cerebritis cns dress emergencies erythematosus hemophagocytic hlh lymphohistiocytosis macrophage mas myelodysplasia
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... SJIA], systemic lupus ... 10,000 ng/mL • Hyponatremia ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... #MDS #Diagnosis ... #Management #treatment ... #hematology #oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Puncture, EEG Treatment ... Maheswaranathan, MD ... CNS #neurology #rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Causes: - Idiopathic ... - Lupus - Leukemia ... Treatment: - Systemic ... #diagnosis #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
extensive skin rash ... Edema in 70% of cases ... disease: symptomatic treatment ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... (MDS) (normal or ... Hypocellular/Hypoplastic MDS ... aplastic anemia Treatment ... Anemia #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... group of disorders caused ... skin that are caused ... Out Secondary Causes ... #diagnosis #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Emergencies Neutropenic ... ): - Hematologic ... Treat underlying cause ... → no immediate treatment ... - CRS: fever, rash
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome ... caused by uncontrolled ... (often termed MAS-HLH ... Treatment Approach ... Diagnosis #Management #Hematology
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