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Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
) - Differential ... AKI: • Hypovolemia ... External obstruction, Neurogenic ... Kidney #Injury #Differential ... #Diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
) - Differential ... : • Hypovolemia ... Nephrolithiasis) • Neurogenic ... #Diagnosis #nephrology ... #causes #algorithm
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Malignancy True hypovolemia ... GI losses • Renal ... • Reduced GFR, AKI ... #Nephrology #Differential
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Malignancy True hypovolemia ... GI losses • Renal ... • Reduced GFR, AKI ... #Nephrology #Differential
Causes of Hypernatremia - Differential Diagnosis
Inadequate water intake:
 • Lack of access to water
Extrarenal hypotonic fluid
Causes of Hypernatremia ... - Differential ... perspiration Renal ... insipidus • Nephrogenic ... #nephrology #sodium
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Losses Non-renal ... vomiting) • Low ... #Differential # ... Diagnosis #Algorithm #nephrology
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
EABV) - Consider: Hypovolemia ... Primary polydipsia, Low ... solute intake, Renal ... #algorithm #causes ... #nephrology
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
renal, and post-renal ... causes. ... Renal causes of ... Kidney #Injury #Differential ... #Sites #Nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... can be high or low ... Present (Uosm ≥100): Hypovolemia ... #differential # ... table #sodium #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Algorithm Extra-renal ... loss (Diarrhea) Renal ... Diagnosis #Algorithm #causes ... #nephrology